A sleepy rat, symbolizing the study of animal sleep patterns

About

Welcome to the homepage of Sleepyrat, a web platform which implements an animal sleep scoring algorithm that is popular amongst research labs.

You can use the platform free of charge by simply signing up with your email address.

Our program takes as input EEG/EMG signals recorded over a certain period of time, e.g. 8-24 hours, and automatically evaluates their sleep dynamics by segmenting EEG/EMGs into 4 sec epochs which are then categorized into either:
(a) One of the three basic vigilance states: wakefulness, NREM, REM
(b) One of three types of artifacts: wake-artifact, NREM-artifact, REM-artifact.

Our machine learning-based method is designed to provide fast, accurate and parameter-free evaluation of animal sleep recordings.
More information can be found here.

Publications that cite our work

A wireless and battery-less implant for multimodal closed-loop neuromodulation in small animals | W Ouyang, W Lu, Y Zhang, Y Liu, JU Kim… - Nature Biomedical …, 20232023
Circadian VIPergic neurons of the suprachiasmatic nuclei sculpt the sleep-wake cycle | B Collins, S Pierre-Ferrer, C Muheim, D Lukacsovich… - Neuron, 20202020
Dopamine pathways mediating affective state transitions after sleep loss | M Wu, X Zhang, S Feng, SN Freda, P Kumari… - Neuron, 20242024
Sleep scoring in rodents: Criteria, automatic approaches and outstanding issues | A Rayan, A Agarwal, A Samanta… - European Journal of …, 20242024
Robust, automated sleep scoring by a compact neural network with distributional shift correction | Z Barger, CG Frye, D Liu, Y Dan, KE Bouchard - PloS one, 20192019
MC-SleepNet: large-scale sleep stage scoring in mice by deep neural networks | M Yamabe, K Horie, H Shiokawa, H Funato… - Scientific reports, 20192019
New Perspectives in Nonintrusive Sleep Monitoring for Neurodegenerative Diseases—A Narrative Review | G Masi, G Amprimo, L Priano, C Ferraris - Electronics, 20232023
Quantitative assessment of resting-state for mild cognitive impairment detection: a functional near-infrared spectroscopy and deep learning approach | D Yang, KS Hong - Journal of Alzheimer's Disease, 20212021
Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome | D Lee, W Chen, HN Kaku, X Zhuo, ES Chao, A Soriano… - Elife, 20232023
High-throughput visual assessment of sleep stages in mice using machine learning | B Geuther, M Chen, RJ Galante, O Han, J Lian… - Sleep, 20222022
Automated scoring of pre-REM sleep in mice with deep learning | N Grieger, JTC Schwabedal, S Wendel, Y Ritze… - Scientific Reports, 20212021
IntelliSleepScorer, a software package with a graphic user interface for automated sleep stage scoring in mice based on a light gradient boosting machine algorithm | LA Wang, R Kern, E Yu, S Choi, JQ Pan - Scientific Reports, 20232023
Purkinje cell dysfunction causes disrupted sleep in ataxic mice | LE Salazar Leon, AM Brown, H Kaku… - Disease Models & …, 20242024
Effect of N-acetylcysteine on sleep: Impacts of sex and time of day | PN Bushana, MA Schmidt, KM Chang, T Vuong… - Antioxidants, 20232023
Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice | LE Salazar Leon, RV Sillitoe - Dystonia, 20232023
Application of machine learning to sleep stage classification | A Smith, H Anand, S Milosavljevic… - 2021 International …, 20212021
Nr-gan: Noise reduction gan for mice electroencephalogram signals | Y Sumiya, K Horie, H Shiokawa… - Proceedings of the 2019 …, 20192019
BDNF-TrkB signaling orchestrates the buildup process of local sleep | W ElGrawani, G Sun, FP Kliem, S Sennhauser… - Cell reports, 20242024
Learning to drop out: An adversarial approach to training sequence vaes | D Miladinovic, K Shridhar, K Jain… - Advances in …, 20222022
Single-nucleus RNA-seq identifies one galanin neuronal subtype in mouse preoptic hypothalamus activated during recovery from sleep deprivation | X Guo, BT Keenan, BC Reiner, J Lian, AI Pack - Cell Reports, 20242024
SDREAMER: Self-distilled mixture-of-modality-experts transformer for automatic sleep staging | J Chen, Y Yao, M Anderson… - … on Digital Health …, 20232023
Closed-loop auditory stimulation method to modulate sleep slow waves and motor learning performance in rats | CG Moreira, CR Baumann, M Scandella… - Elife, 20212021
A novel machine learning system for identifying sleep–wake states in mice | JJ Fraigne, J Wang, H Lee, R Luke, SK Pintwala… - Sleep, 20232023
A deep learning algorithm for sleep stage scoring in mice based on a multimodal network with fine-tuning technique | K Akada, T Yagi, Y Miura, CT Beuckmann… - Neuroscience …, 20212021
SlumberNet: deep learning classification of sleep stages using residual neural networks | PK Jha, UK Valekunja, AB Reddy - Scientific Reports, 20242024
Establishment of a chronic insomnia rat model of sleep fragmentation using unstable platforms surrounded by water | DQ Yan, XP Zhang, WH Zhang… - Experimental and …, 2023 - spandidos2023
Down‐phase auditory stimulation is not able to counteract pharmacologically or physiologically increased sleep depth in traumatic brain injury rats | CG Moreira, P Hofmann, A Müllner… - Journal of Sleep …, 20222022
Workflow for the unsupervised clustering of sleep stages identifies light and deep sleep in electrophysiological recordings in mice | R Cusinato, S Gross, M Bainier, P Janz… - Journal of Neuroscience …, 20242024
An attention-based temporal convolutional network for rodent sleep stage classification across species, mutants and experimental environments with single-channel … | Y Liu, Z Yang, Y You, W Shan… - Physiological …, 20222022
Pupil dynamics-derived sleep stage classification of a head-fixed mouse using a recurrent neural network | G Kobayashi, KF Tanaka, N Takata - The Keio Journal of Medicine, 20232023
An artificial neural network for automated behavioral state classification in rats | JG Ellen, MB Dash - PeerJ, 20212021
Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice | LES Leon, RV Sillitoe - BioRxiv, 20232023
An automated sleep staging tool based on simple statistical features of mice electroencephalography (EEG) and electromyography (EMG) data | RG Yamada, K Matsuzawa, KL Ode… - European Journal of …, 20242024
Sleep-Wake Rhythm and Oscillatory Pattern Analysis in a Multiple Hit Schizophrenia Rat Model (Wisket) | LG Adlan, M Csordás-Nagy, B Bodosi… - Frontiers in Behavioral …, 20222022
A real‐time sleep scoring framework for closed‐loop sleep manipulation in mice | D Huffman, A Ajwad, F Yaghouby… - Journal of Sleep …, 20212021
WaveSleepNet: An interpretable deep convolutional neural network for the continuous classification of mouse sleep and wake | K Kam, DM Rapoport, A Parekh, I Ayappa… - Journal of neuroscience …, 20212021
Identification of the sleep–wake states in rats using the high‐frequency activity of the electroencephalogram | M Silva‐Pérez, A Sánchez‐López… - Journal of Sleep …, 20212021
Влияние клозапина и 5-НТ2А-антагониста РУ-31 на электроэнцефалограмму и двигательную активность крыс в модели шизофрении с … | КЮ Калитин, ГВ Придворов, АА Спасов… - Кубанский научный …, 20222022
Sleep-Deep-Learner is taught sleep–wake scoring by the end-user to complete each record in their style | F Katsuki, TJ Spratt, RE Brown, R Basheer… - Sleep …, 20242024
Sleep-Deep-Net learns sleep wake scoring from the end-user and completes each record in their style | F Katsuki, TJ Spratt, RE Brown, R Basheer, DS Uygun - bioRxiv, 20232023
Novel murine closed-loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration | I Dias, S Kollarik, M Siegel, CR Baumann, CG Moreira… - bioRxiv, 20242024
Cerebellar deep brain stimulation as a dual function therapeutic for restoring movement and sleep in dystonic mice | LES Leon, LH Kim, RV Sillitoe - bioRxiv, 20232023
Evaluating the Influence of Temporal Context on Automatic Mouse Sleep Staging through the Application of Human Models | JG Ciudad, M Mørup, BR Kornum, AN Zahid - arXiv preprint arXiv …, 20242024
Sleep identification enabled by supervised training algorithms (SIESTA): an open-source platform for automatic sleep staging of rodent polysomnographic data | CS Caldart, REA Sanchez, M Ben-Hamo, AI Beck… - BioRxiv, 20202020
Chronic dietary supplementation with nicotinamide riboside reduces sleep need in the laboratory mouse | PN Bushana, MA Schmidt, MJ Rempe, BA Sorg… - Sleep …, 20232023
Validation of Deep Learning-based Sleep State Classification | W Chen, X Zhang, H Miao, MJ Tang… - microPublication …, 20222022
Natural age-related sleep-wake alterations onset prematurely in the Tg2576 mouse model of Alzheimer's disease | S Kollarik, CG Moreira, I Dias, D Bimbiryte… - bioRxiv, 20212021
Somnotate: A probabilistic sleep stage classifier for studying vigilance state transitions | PJN Brodersen, H Alfonsa, LB Krone… - PLOS Computational …, 20242024
Automated Sleep Stage Scoring Using* k*-Nearest Neighbors Classifier | T Kiss, S Morairty, M Schwartz, S Thomas… - Journal of Open …, 20202020
The Role of Posttranscriptional Gene Regulation During Homeostatic Synaptic Plasticity: Neuroscience | D Colameo - 2023 - research2023
Sleep is important: How circadian-timed trauma keeps mice up at day and the societal implications that keep me up at night | AI Beck - 20232023
Exploring Relationships between Cerebral and Peripheral Biosignals with Neural Networks | AH Hatteland, R Marcinkevičs… - … on Digital Health …, 20212021
Co-Loss Function for Rodents Sleep Stage Scoring Based on Single-Channel EEG | S Chang, Y You - 2022 China Automation Congress (CAC), 20222022
Dopaminergic Modulation of Affective State and Behavior | M Wu - 20222022
Closed-loop auditory modulation of slow waves: development and application in healthy and traumatic brain injury rats | C Gonçalves Moreira - 2021 - research2021
Postmortem tissue changes and dynamics of their impedance parameters: a preclinical experimental study | OS Lavrukova, EL Kazakova… - Kuban Scientific Medical …, 20232023
Посмертные изменения тканей и динамика их импедансометрических показателей: доклиническое экспериментальное исследование | ОС Лаврукова, ЕЛ Казакова… - Кубанский научный …, 20232023
Machine Learning Approach for Vigilance State Classification in Mice | A Muhury - 20212021
Machine Learning approaches in Neuroscience: behavioral and sleep classification | R Cusinato2021
Mechanisms of Sleep-Dependent Memory Consolidation in the Rodent Prefrontal Cortex | BH Harper - 20202020
Sleeping on the Job: How studying sleep and circadian rhythm disturbances in a mouse model of Dravet syndrome kept me up at night | R Sanchez - 20202020
Robust, automated sleep scoring by a compact neural network with distributional shift | Z Barger - 20202020